The investigation of hypercalcemia.
نویسندگان
چکیده
Aetiology and pathogenesis A large number of diseases can lead to hypercalcaemia (table). In most instances the underlying cause is either primary hyperparathyroidism or malignant disease; the many other causes are rarely encountered even within specialist units. The prevalence of primary hyperparathyroidism and hypercalcaemia of malignancy varies with the population sampled. In ambulant subjects in the community who were found to be hypercalcaemic as part of a screening programme, 86% were ultimately shown to have primary hyperparathyroidism and only 2% malignant disease.' The findings in hypercalcaemic inpatients are different: 58% of patients have malignant disease and 33% primary hyperparathyroidism. Indeed, primary hyperparathyroidism is one of the most common endocrine diseases with a prevalence of around 1-3 per thousand, exceeded only by diabetes mellitus and thyroid disease.
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عنوان ژورنال:
- Journal of clinical pathology
دوره 47 11 شماره
صفحات -
تاریخ انتشار 1994